Quinazoline based EGFR inhibitors containing a zinc binding moiety

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专利权人:

Curis; Inc.

发明人:

Zhai, Haixiao,Cai, Xiong,Gould, Stephen,Qian, Changgeng

申请号：

AU2007296746

公开号：

AU2007296746B2

申请日:

2007.09.10

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention relates to quinazoline containing zinc-binding moietybased derivatives that have enhanced and unexpected properties as inhibitorsof epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their usein the treatment of EGFR-TK related diseases and disorders such as cancer. Thesaid derivatives may further act as HDAC inhibitors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/