LUGOVSKOY, ALEXEY A.,TAYLOR, FREDERICK R.,MCLACHLAN, KAREN
申请号:
CA2794863
公开号:
CA2794863C
申请日:
2011.04.15
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
This invention relates to recombinant antibody molecules, or alpha-4 bindingfragments thereof, that bind to VLA-4, wherein the antibodies are derived frommouseantibody HP1/2, human framework sequences, and back mutations at specificframeworkpositions.