The instant invention provides crystalline forms of (S,E)-4-(2-(3-(3-chloro-2-fluoro-6-(1H-tetrazol-1-yl)phenyl)acr yloyl)-5-(4-methyl-2-oxopiperazin-1-yl)-1,2,3,4-tetrahydroisoqui noline-1-carboxamido)benzoic acid and its solvates thereof； processes for the production of such crystalline forms； pharmaceutical compositions comprising such crystalline forms； and methods of treating thromboembolic disorders with such crystalline forms or such pharmaceutical compositions.La presente invención se refiere a formas cristalinas de ácido (S,E)-4-(2-(3-(3-cloro-2-fluoro-6-(1H- tetrazol-1-il)fenil)acriloi l)-6.-(4-metil-2-oxopiperazin-1- il) -1,2,3,4-tetrahidroisoquinoli na-1-carboxamida) benzoico y sus solvatos del mismo； procesos para la producción de tales formas cristalinas； composiciones farmacéuticas que comprenden tales formas cristalinas； y métodos para tratar trastornos tromboembólicos con tales formas cristalinas o tales composiciones farmacéuticas.
