Disclosed herein is a kind of dermatologic object, is to prepare containing vitamine D3 compound and corticosteroid as active constituent, that is, each active constituent of excellent in stability, and the percutaneous absorbtion of active constituent appropriate. Composition includes for skin non-aqueous composition: (one) Maxacalcitol (2) it includes betamethasone and its ester that at least one corticosteroid, which is selected from, C, it is 0. that at least low polarity ester oil, which has IOB values,07 or more, than 0.20 Only a little and (II) at least one nonpolar liquid solvent.
