Embodiments of the present disclosure include materials and methods relating to sterilization devices. In certain embodiments, materials and methods disclosed herein relate to pre-surgical sterilization of an appendage of a subject using a device that reduces surgical preparation time and microbial growth. Certain embodiments of the present disclosure disclose materials and methods to ameliorate high costs associated with medical care, especially the utilization of costly elective hospital services, by for example reducing operating room costs and increasing efficiency without compromising patient health. Particularly disclosed is a sterilization device comprising a multilayered transparent sleeve, an absorbent foam insert positioned within said sleeve and configured for placement against an area of a subjects body, wherein said insert also comprises a plurality of sterilization sacs containing one or more sterilization agents, stabilization mechanisms for securing the sterilization device to the subjects body and wherein at least one of the plurality of sterilization sacs is configured to release the one or more sterilization agents upon application of pressure to the sterilization sac onto the area of a subjects body in need of medical treatment.Des modes de réalisation de la présente invention comprennent des matériaux et des procédés se rapportant à des dispositifs de stérilisation. Dans certains modes de réalisation, les matériaux et les procédés de linvention se rapportent à stérilisation préopératoire dun appendice dun sujet au moyen dun dispositif qui réduit la durée de préparation chirurgicale et la croissance microbienne. Certains modes de réalisation de la présente invention concernent des matériaux et des procédés permettant de réduire les coûts élevés associés aux soins médicaux, en particulier lutilisation de services hospitaliers facultatifs coûteux, par exemple, par réduction des coûts de salle dopération et augmentation de lefficacité sans compromet
