Regents of the University of Minnesota;National Health Research Institutes
发明人:
申请号：
EP16842462.0
公开号：
EP3344997A4
申请日:
2016.06.15
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Disclosed is an in vitro screening method for identifying an antagonist-to-agonist allosteric modifier of a mu-opioid receptor and an in vivo method for confirming that a test compound is such a modifier of a mu-opioid receptor. Also disclosed is a method for treating an opioid receptor-associated condition using a compound of Formula (I) and a pharmaceutical composition containing the same.
