Systems and methods for detecting substances using a wearable oral device are described. For example, a wearable device is described comprising a mouth guard, a sensor coupled to the mouth guard and being configured to detect chemical signals, and a transmitter coupled to the sensor and being configured to transmit the detected chemical signals to a receiver. In another example, a wearable device is described comprising a bond being configured to be removably attachable to a tooth of a user, a sensor coupled to the bond and being configured to detect chemical signals, and a transmitter coupled to the sensor and being configured to transmit the detected chemical signals to a receiving device.