The invention discloses a physiological signal detection device.Including: a pressure sensing module and a micro control processing module.The pressure sensing module has a first pressure sensing unit and a second pressure sensing unit.They are attached to two different positions of organisms.To detect a first physiological signal and a second physiological signal,And after the signal conversion,A first voltage signal and a second voltage signal can be generated.After signal processing of the first voltage signal and the second voltage signal,A first continuous pulse and a second continuous pulse are generated.The time difference between the first selected waveform reference point of the first continuous pulse wave and the second selected waveform reference point of the second continuous pulse wave is used.Calculate the transmission time of one pulse wave,As a basis of blood pressure information calculation.本創作揭露一種生理訊號偵測裝置,包括:一壓力感測模組及一微控制處理模組,壓力感測模組具有一第一壓力感測單元及一第二壓力感測單元,其分別貼附於生物體之兩相異位置,以偵測一第一生理訊號及一第二生理訊號,並於訊號轉換後,可生成一第一電壓訊號及一第二電壓訊號,微控制處理模組用以對第一電壓訊號及第二電壓訊號進行訊號處理後,生成一第一連續脈搏波及一第二連續脈搏波,並以第一連續脈搏波的一第一選定波形參考點及一第二連續脈搏波的第二選定波形參考點之間的時間差,運算出一脈搏波傳遞時間,以作為一血壓資訊之運算依據。