CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO)
发明人:
JOAQUÍN PASTOR FERNÁNDEZ,JULEN OYARZABAL SANTAMARINA,SONIA MARTÍNEZ GONZALES
申请号：
BRPI1014572
公开号：
BRPI1014572A2
申请日:
2010.04.16
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
