Julen Oyarzabal Santamarina;Joaquin Pastor Fernández;Sonia Martínez Gonzalez
发明人:
Joaquin Pastor Fernández,Sonia Martínez Gonzalez,Julen Oyarzabal Santamarina
申请号:
US13264544
公开号:
US20120083492A1
申请日:
2010.04.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.