COMPOUNDS, PHARMACEUTICAL COMPOSITION, AND METHODS OF INHIBITING NS3 / NS4 PROTEASE ACTIVITY, HEPATIC FIBROSIS TREATMENT AND HEPATIC FUNCTION INTENSIFICATION IN AN INDIVIDUAL HAVING HEPATITIS C VIRUS INFECTION.
STEVEN W. ANDREWS,SCOTT SEIWERT,LEONID BEIGELMAN,LAWRENCE BLATT,BRAD BUCKMAN,YUTONG JIANG,ROBERT J. KAUS,APRIL L. KENNEDY,TIMOTHY S. KERCHER,MICHAEL A. LYON,BIN WANG,KEVIN R. CONDROSKI
申请号:
BRPI0811447
公开号:
BRPI0811447A2
申请日:
2008.05.09
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula II, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.