The present invention relates to diarylpyridazinone derivatives that block the potassium Kv channels (specifically the Kv1.5, Kv4.3, and Kv11.1 channels) and to the use thereof for the treatment of humans. Said compounds have the general formula (I), where R1 and R2 are simultaneously or independently one or more groupings such as: halogen, such as F, Br, Cl, a straight or branched C1-C4 alkyl, hydroxy, a straight or branched C1-C4 alkoxy, arylsulfonamido, in which the aryl is optionally replaced with a straight or branched C1-C4 alkyl, or nitrile, as well as the various enantiomers and the mixtures thereof in any proportion, and the pharmaceutically acceptable salts thereof.Jedinjenja opšte formule I: gde R1 i R2 simultano ili nezavisno predstavljaju jednu ili nekoliko grupa odabranih od: halogena kakvi su F, Br, Cl, linearne ili razgranate C1-C4 alkil, hidroksi, linearne ili razgranate C1-C4 alkoksi, nitril ili arilsulfonamido, čiji je aril po želji supstituisan linearnom ili razgranatom C1-C4 alkil grupom, kao i različiti enantiomeri i njihove smese u svim proporcijama, i njihove farmaceutski prihvatljive soli. Prijava sadrži još 8 patentnih zahteva.