Cantwell, Mark J.,Chan, Winnie M.,Ewald, Brett,Robbins, Joan M.
申请号：
AU2017379835
公开号：
AU2017379835A1
申请日:
2017.12.19
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Disclosed are replication-competent oncolytic adenoviruses, comprising chimeric human/mouse CD40 ligands. The oncolytic adenoviruses may be replication competent. The chimeric human/mouse CD40 ligand may be MEM40. Also disclosed are methods comprising administering a replication competent oncolytic adenovirus armed with at least one chimeric human/mouse CD40 ligand, for example MEM40, to a patient suffering from a cancer.
