Stephen K. Franzyshen;Steven R. Cosentino;Peter N. Nugara;Daniel C. Sanders;Fenghua Deng;Bruce C. Begnoche;Christine A. Creegan
发明人:
Peter N. Nugara,Bruce C. Begnoche,Stephen K. Franzyshen,Fenghua Deng,Daniel C. Sanders,Christine A. Creegan,Steven R. Cosentino
申请号：
US12890291
公开号：
US08840920B2
申请日:
2010.09.24
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer； (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer； and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer.A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
