MATTEO IANNACONE U S A,ULRICH VON ANDRIAN U S A,OMID C FAROKHZAD U S A,FRANK ALEXIS U S A,PAMELA BASTO U S A,JINJUN SHI U S A,ELLIOTT ASHLEY MOSEMAN U S A,ROBERT LANGER U S A,ELENA TONTI ITALY
申请号:
IN3540/DELNP/2011
公开号:
IN2011DN03540A
申请日:
2011.05.12
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention pro-vides compositions and systems for delivery of nanocarriers to cells of the immune sys-tem. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an im-munofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention pro-vides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof For example, the present invention describes nanocarriers ca-pable of eliciting an immune response and the production of anti-nicotine antibodies.