Matteo Iannacone,Ulrich von Andrian,Omid C. Farokhzad,Frank Alexis,Pamela Basto,Jinjun Shi,Elliott Ashley Moseman,Robert S. Langer,Elena Tonti
申请号:
US13123886
公开号:
US08932595B2
申请日:
2009.10.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention provides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof. For example, the present invention describes nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.