KIM SEON JIN,김선진,KIM YOUNG JU,김영주,YEON YOUNG EUN,연영은,HAN BEOM KU,한범구,KIM HYUN IL,김현일,PARK CHARL SE,박철세
申请号：
KR1020170176343
公开号：
KR1020180075410A
申请日:
2017.12.20
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a novel bacteriophage SH9 having a killing ability specific to Salmonella, particularly Salmonella hadar a pharmaceutical composition, an antibiotic composition, a feed additive composition, a feed, a disinfectant or a washing agent for preventing or treating infectious diseases caused by Salmonella, which all include the bacteriophage and a method for preventing or treating infectious diseases caused by Salmonella, which includes a step of administrating the bacteriophage to an object. The method for preventing or treating infectious diseases caused by Salmonella using the bacteriophage SH9 has very high specificity to Salmonella compared to a conventional chemical material such as antibiotics or the like, and the bacteriophage SH9 is infected to Salmonella to proliferate 100 times or more in the Salmonella, thereby having excellent bacteriolytic activity and being strong to physiochemical stimulation. In addition, the bacteriophage SH9 of the present invention is not infected to a host other than bacteria except a human, an animal, a plant, or the like, and thus it is possible to solve a problem of antibiotic resistant bacteria due to abuse of antibiotics, a problem of residual antibiotics in food, and a problem of a wide range of host ranges. Accordingly, the bacteriophage SH9 of the present invention can be variously used in the fields of prevention or treatment of infectious diseases caused by pathogenic Escherichia coli, antibiotic compositions, feed additive compositions, feeds, disinfectants, or washing agents.본 발명은 살모넬라균, 특히 살모넬라 하다(Salmonella Hadar)에 특이적인 사멸능을 갖는 신규 박테리오파지 SH9, 상기 박테리오파지를 포함하는 살모넬라균에 의한 감염성 질병의 예방 또는 치료용 약학적 조성물, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 SH9을 이용한 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 살모넬라균에 대한 특이성이 매우 높고, 상기 박테리오파지 SH9은 살모넬라균에 감염하여 살모넬라균 내에서 100배 이상 증식함으로써 용균 활성이 우수하고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명
