Provided herein are compositions comprising an herbal extract of a mixture of Radix Rehmanniae, Fructus Corni Officinalis, Radix Dioscoreae Oppositae, Sclerotium Poriae Cocos, Cortex Moutan Radicis, Rhizoma Alismatis Orientalis, Anemarrhena Rhizome, Glycyrrhiza uralensis, Radix Astragali, and Atractylodis Macrocephalae Rhizoma. The invention also relates to a method of treating hot flashes associated with peri-menopause, menopause, or post-menopause, a method of reducing total cholesterol and/or lowering low density lipoprotein (LDL) levels and a method of reducing weight and/or body mass index (BM I) using the above mentioned herbal extract.