INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;THERAVECTYS
发明人:
Pierre Charneau,Anne-Sophie Beignon,Frederic Philippe Coutant,Karine Courbeyrette
申请号:
US14197532
公开号:
US09328146B2
申请日:
2014.03.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to the design of gene transfer vectors and especially provides lentiviral gene transfer vectors suitable for either a unique administration or for iterative administration in a host, and to their medicinal application (such as vaccination against Immunodeficiency Virus, especially suitable in human hosts). Gene transfer vectors can be either integrative or non-integrative vectors. The invention encompasses prophylactic, therapeutic, symptomatic, and curative treatments of animals, including humans, as well as gene therapy and vaccination in vivo.