A system and method are provided for generating and delivering a volumetric modulated arc therapy (“VMAT”) plan to a patient. In some aspects, the method includes receiving a representation of a patient comprising information related to target and non-target volumes of interest and generating an objective function based on the representation of the patient. The method also includes performing an iterative optimization process using the objective function to generate a VMAT plan and generating a report according to the VMAT plan.
