The utility model provides an electric inter-tooth brush which comprises a connecting rod, a rotating shaft, a shaft sleeve, a fixing sleeve, a spring, a locking sleeve, and an inter-tooth brush used for cleaning dental plaque on teeth, wherein the fixing sleeve is arranged in a groove in the front end of the connecting rod; the shaft sleeve is arranged in the connecting rod; the rotating shaft penetrates through the shaft sleeve and the fixing sleeve and is in clearance fit with a side wall of the connecting rod; the locking sleeve can move up and down and is arranged on the fixing sleeve in a sleeving manner; the spring is arranged between the fixing sleeve and the locking sleeve; the inter-tooth brush is detachably arranged on the fixing sleeve; a first bulge is formed in the lower end of the inter-tooth brush; a cavity matched with the first bulge is formed in the fixing sleeve; and the other end of the rotating shaft sleeves with the motor. The electric inter-tooth brush disclosed by the utility model is simple in structure, is convenient to replace, is driven by the motor and is conveniently used by consumers, the cleaning frequency is improved, the inter-tooth space is clean, and vibratory massage of the gingiva is increased.