The object of the present invention is to propose a composition which can inhibit fatty liver and kidney hypertrophy caused by diabetes by containing earthworm as an effective component.A composition for inhibiting fatty liver and kidney hypertrophy caused by diabetes. The composition is obtained as follows: inoculating vegetable and fruit extracts with yeast to obtain fermentation liquid, mixing earthworm into the fermentation liquid, fermenting the earthworm, obtaining fermentation earthworm, mixing Tianqi into the fermentation earthworm, fermenting and drying the earthworm to obtain fermentation mixture, mixing ant and Ginkgo leaves, thereby obtaining the composition.本發明的目的在於提出一種組合物，其通過含有蚯蚓作爲有效成分而抑制由糖尿病引起的可能性高的脂肪肝和腎肥大。一種抑制由糖尿病引起的脂肪肝和腎肥大的組合物，該組合物如下獲得：對蔬果提取物接種酵母而得到發酵液，向該發酵液中混入蚯蚓，使該蚯蚓發酵，由此得到發酵蚯蚓，向該發酵蚯蚓中混合田七，使其發酵乾燥而得到發酵混合物，向該發酵混合物中混合螞蟻和銀杏葉，由此得到該組合物。
