Jonathan Robert Coppeta,Kenneth N. Horne,John T. Santini, Jr.,John A. Scholl,Gregory J. R. Spooner,Cynthia L. Stevenson,Naveed Shams,Andrew Poutiatine
申请号:
US13023370
公开号:
US08911426B2
申请日:
2011.02.08
申请国别(地区):
US
年份:
2014
代理人:
摘要:
An implantable drug delivery device that uses multiple reservoir elements to contain and release doses of active pharmaceutical ingredients. The device includes a first shell element, which has a first enclosed cavity volume and forms a low-permeability barrier. The first shell element is configured to absorb light irradiation from a laser source, the laser irradiation causing a breach in the first shell element. A first active pharmaceutical ingredient is contained in the first enclosed cavity volume and is released when the first shell element is breached. The device also includes a second shell element, which has a second enclosed cavity volume and also forms a low-permeability barrier. A second active pharmaceutical ingredient is contained in the second enclosed cavity volume. The device also includes an envelope element containing the first and second shell elements.