Donald Y. M. Leung;Jane A. Gross;Janine M. Bilsborough
发明人:
Donald Y. M. Leung,Janine M. Bilsborough,Jane A. Gross
申请号:
US13094482
公开号:
US08388964B2
申请日:
2011.04.26
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to methods of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cell. In particular, diseases or disorders including contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous T cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, and herpes simplex virus, or combination thereof will benefit from the administration of an IL-31 antagonist. The invention also includes methods of predicting a therapeutically responsive patient population.