ZYMOGENETICS; INC.;NATIONAL JEWISH MEDICAL RESEARCH CENTER;ZYMOGENETICS, INC.
发明人:
DONALD Y.M. LEUNG,JANINE M. BILSBOROUGH,JANE A. GROSS
申请号:
US13754278
公开号:
US20130177563A1
申请日:
2013.01.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to methods of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cell. In particular, diseases or disorders including contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous T cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, and herpes simplex virus, or combination thereof will benefit from the administration of an IL-31 antagonist. The invention also includes methods of predicting a therapeutically responsive patient population.