WHITE PLEUROPTERUS MULTIFLORUS AND PHLOMIS UMBROSA EXTRACT FOR PROMOTING INSULIN-LIKE GROWTH FACTOR SECRETION AND BONE FRAMEWORK GROWTH, AND METHOD FOR PRODUCING THE SAME
PURPOSE: Pleuropterus multiflorus and Phlomis umbrosa extracts and producing methods thereof are provided to mass-produce a water-soluble extract containing glycoside derived from Pleuropterus multiflorus and Phlomis umbrosa. CONSTITUTION: A producing method of a Pleuropterus multiflorus extract comprises the following steps: mixing 80-100 deg C water with Pleuropterus multiflorus, and stirring and extracting the Pleuropterus multiflorus for 6-10 hours before cooling the obtained extract at 70 deg C: inserting 4-5wt% of alpha-amylase enzyme into the Pleuropterus multiflorus extract, and fermenting the mixture at 70-80 deg C for 2-3 hours； heating the Pleuropterus multiflorus extract at 95-99 deg C, and rapidly cooling the extract for stopping the activity of the alpha-amylase enzyme； separating solid parts from the Pleuropterus multiflorus extract using a centrifugal dehydrator or a filter press, and centrifugal separating the Pleuropterus multiflorus extract using an ultrahigh speed centrifuge； passing the firstly refined Pleuropterus multiflorus extract through an active carbon filter； passing the secondly refined Pleuropterus multiflorus extract through a micro or ultra filtering system for separating the extract into retentate and permeate； collecting the permeate, and diluting the retentate with purified water； repeating the filtering processes for 2-9 times； and concentrating the Pleuropterus multiflorus extract before freeze-drying. [Reference numerals] (AA) Hypothalamus； (BB) Growth hormone releasing hormone； (CC) Somastatin； (DD) Vegetable glycoside(promoting the secretion； (EE) Pituitary gland； (FF) Amino acid(promoting the secretion)； (GG) Growth hormone； (HH) Liver/other tissues； (II) IGF-1； (JJ) Stimulation； (KK) Control본 발명은 인슐린 유사 성장인자 분비능 증강 및 뼈 골격 성장 촉진 효능이 있는 백하수오와 속단의 배당체 성분을 주성분으로 하는 수용성 추출 정제 물질 및 그 제조방법에 관한 것이다.
