您的位置: 首页 > 农业专利 > 详情页

SUBSTITUTED PHENOXY N-ALKYLATED THIAZOLIDINEDIONE AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS
专利权人:
JANSSEN PHARMACEUTICA N.V.
发明人:
GAUL, MICHAEL,SEARLE, LILY LEE,RENTZEPERIS, DIONISIOS
申请号:
NZ57941808
公开号:
NZ579418A
申请日:
2008.03.06
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are substituted phenoxy N-alkylated thiazolidinediones represented by general formula (I), or optical isomers, enantiomers, diastereomes, cis-trans isomers, racemates or pharmaceutically acceptable salts thereof, such as 4-{ 2-Methoxy-4-[3-(2-morpholin-4-yl-ethyl)-2,4-dioxo-thiazolidin-5-ylidenemethyl]-phenoxy} -3-trifluoromethyl-benzonitrile. Also disclosed is the use of the compounds of formula (I) for treating a disease, disorder or condition such as bone-related disease, bone formation, cartilage formation, cartilage loss, cartilage degeneration, cartilage injury, ankylosing spondylitis, chronic back injury, gout, osteoporosis, osteolytic bone metastasis, multiple myeloma, chondrosarcoma, chondrodysplasia, osteogenesis imperfecta, osteomalacia, Paget's disease, polymyalgia rheumatica, pseudogout, arthritis, rheumatoid arthritis, infectious arthritis, osteoarthritis, psoriatic arthritis, reactive arthritis, childhood arthritis, Reiter's syndrome, and repetitive stress injury.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充