Jih Ru Hwu,Yu-Sern Lin,Chen-Sheng Yeh,Dar-Bin Shieh,Wu-Chou Su
申请号:
US13548856
公开号:
US20120282327A1
申请日:
2012.07.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A phosphate-containing nanoparticle delivery vehicle includes nanoparticle, an active ingredient, and a phosphodiester moiety connecting the nanoparticle and the active ingredient and forms a prodrug. The nanoparticle delivery vehicle achieves the function of increasing hydrophilicity of the active ingredient and specificity against tumor cells. Advantages of the nanoparticle material include biocompatibility, magnetism and/or controllable drug release.