COMPOSITIONS NANOPARTICULAIRES COMPRENANT DES DERIVES INHIBITEURS DE LA HMG-COA REDUCTASE (STATINES), LEURS COMBINAISONS AINSI QUE LA FABRICATION DE CES COMPOSITIONS PHARMACEUTIQUES
COOPER, EUGENE R.,HOVEY, DOUGLAS,CARY, GRETA,LINDNER, MARIE,LIVERSIDGE, ELAINE,LIVERSIDGE, GARY G.,RYDE, TUULA
申请号：
CA2488499
公开号：
CA2488499C
申请日:
2003.06.10
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention is directed to nanoparticulate compositions comprisingstatin such as lovastatin or simvastatin including surface stabilizer. Thestatin particles of the composition have an effective average particle size ofless than about 2000 nm. In another aspect of this invention, novelcombinations of statins and other cholesterol lowering agents are describedand methods of using same are taught.
