PETERS, KEVIN,SHALWITZ, ROBERT,JANUSZ, JOHN,SMITH, ALEXANDER
申请号:
EP14762974
公开号:
EP2967066A4
申请日:
2014.03.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.