Kevin Peters,Robert Shalwitz,John Janusz,Alexander Smith
申请号:
US15969109
公开号:
US20180251457A1
申请日:
2018.05.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.