The present invention provides an artificial valve forming base material and a prosthetic valve which make it easy for penetration of connective tissue into an leaf formation space to shorten the time required for forming leaflets. Specifically, a columnar substrate body 6 is provided. A plurality of recesses 7 are formed on the outer peripheral surface of the substrate body 6. The cover base material 9 is attached to the base material main body 6. The recessed portion 7 is covered with the cover base material 9 to constitute the leaf formation space 8. An entry port 10 of the connective tissue 2 is formed between the edge of the cover substrate 9 and the outer edge of the recess 7. A slit 11 is formed in the cover base material 9 to make the leaf formation space 8 communicate with the outside of the base material. The slit 11 is formed to have a length parallel to the base material center axis 15 and reaching the edge of the cover base material 9. The artificial valve forming base 1 is placed in the environment where biological tissue material is present. Thereby forming a connective tissue 2 on the surface of the substrate. The cover base material 9 is pulled out from the base material main body 6 in the direction of the center axis of the base material. The connective tissue 2 taken out from the base material is referred to as a prosthetic valve 5.本発明は、弁葉形成空間に結合組織を侵入させやすくして、弁葉の形成に要する時間を短くすることのできる人工弁形成基材、及び人工弁を提供するものである。具体的には、柱状の基材本体6を設ける。基材本体6の外周面に複数の凹部7を形成する。基材本体6にカバー基材9を装着する。カバー基材9で凹部7を覆って弁葉形成空間8を構成する。カバー基材9の端縁と凹部7の外縁との間に結合組織2の侵入口10を構成する。カバー基材9にスリット11を形成して弁葉形成空間8と基材外部とを連通させる。スリット11を基材中心軸15と平行かつカバー基材9の端縁に至る長さに形成する。人工弁形成基材1を生体組織材料の存在する環境に設置する。基材表面に結合組織2を形成する。カバー基材9を基材本体6から基材中心軸方向に抜き出す。基材から取り出した結合組織2を人工弁5とする。
