Lee, William W.,Lu, Feng,Min, Yin,Shao, Liuying,She, Hao,Shen, Zhou
申请号:
AU2010339907
公开号:
AU2010339907A1
申请日:
2010.12.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides a pharmaceutical composition for oral drug delivery comprising a solid dosage form containing an effective amount of a therapeutic agent, a permeation enhancer and a pharmaceutically acceptable excipient and a bioadhesive layer containing a bioadhesive polymer, and optionally comprising an impermeable or semi-permeable layer having an opening capable of directing a unidirectional release of the therapeutic agent and the permeation enhancer from the solid dosage form. Methods of making and using the present pharmaceutical composition are also provided.