Peptide derivatives that control thymic stromal lymphopoietin-mediated signal transmission and pharmaceutical compositions for preventing and treating allergic and asthmatic diseases containing the same
The present invention relates to a peptide derivative that controls thymic stromal lymphopoietin-mediated signal transmission, and a pharmaceutical composition for preventing and treating allergic and asthmatic diseases including the same, and more specifically, a peptide derivative represented by Formula 1 And a pharmaceutical composition for the prevention and treatment of allergies and asthma diseases containing the same. According to the present invention, a peptide derivative capable of effectively suppressing formation of an inflammatory reaction in allergy or asthma disease and a pharmaceutical composition containing the peptide derivative are provided, and various allergy and asthma diseases are fundamentally prevented or treated using the peptide derivative. be able to.本発明は、胸腺間質リンホポエチン媒介信号伝逹を制御するペプチド誘導体、及びこれを含むアレルギー及び喘息疾患の予防及び治療用薬学組成物に関し、より具体的には、化学式1で表示されるペプチド誘導体、及びこれを含むアレルギー及び喘息疾患の予防及び治療用薬学組成物に関する。本発明によると、アレルギー或いは喘息疾患の炎症反応形成を効果的に抑制できるペプチド誘導体及びこれを含む薬学組成物が提供され、これを用いて多様なアレルギー及び喘息疾患を根本的に予防又は治療することができる。