In the inspection area of the inspection object, or biological properties mechanical, physical, chemical, and / or determination of the spatial resolution of the state variables, and / or mechanical, physical, and chemical invention, / or the step of turning on the magnetic particles to at least a portion of a) the examination area changes in the state variables or biological properties, b) In the inspection area, so as to produce a partial area of the second with the intensity of the high field portion first area with the strength of lower magnetic field, and wherein using the spatial profile of the strength of the magnetic field step of generating a magnetic field, so as to rotate some or vibration of at least c) the magnetic particles, the step of generating at least partially rotating magnetic field or vibration superimposed in part area of the first with the strength of the low magnetic field, step of irradiating electromagnetic radiation to the test area using a radiation source of at least one d), detecting said electromagnetic radiation which has been reflected and / or scattered by using one detector and at least e), and the reflected and / or on how to do with the intensity of the electromagnetic radiation scattered, the step of determining the polarization and / or absorb. Moreover, the present invention further relates to a method for determining the spatial resolution of the state variables and these properties using the device according to the invention the present invention. The invention further relates to a magnetic particle composition having improved properties for imaging the magnetic particles, to the optical contrast composition.本発明は、検査対象物の検査エリアにおける、機械的、物理的、化学的及び/又は生物学的な特性又は状態変数の空間分解の決定、及び/又は機械的、物理的、化学的及び/又は生物学的な特性又は状態変数の変化をa)前記検査エリアの少なくとも一部に磁性粒子を投入するステップ、b)前記検査エリアにおいて、低い磁場の強さを持つ第1の部分エリアと高い磁場の強さを持つ第2の部分エリアとを生成するように、磁場の強さの空間プロファイルを用いて前記磁場を生成するステップ、c)前記磁性粒子の少なくとも幾つかが振動又は回転するように、低い磁場の強さを持つ前記第1の部分エリアにおいて重ねられた振動又は回転磁場を少なくとも部分的に生成するステップ、d)少なくとも