Taoda, Yoshiyuki,Johns, Brian Alvin,Kawasuji, Takashi,Taishi, Teruhiko
申请号：
AU2006239177
公开号：
AU2006239177B8
申请日:
2006.04.28
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention is to provide a novel compound (I), having the anti-virusactivity, particularly the HIV integrase inhibitory activity, and a drug containingthe same, particularly an anti-HIV drug, as well as a process and an intermediatethereof. Compound (I) wherein Z is NR； R ishydrogen or lower alkyl； X is a single bond, a hetero atom group selected from O,S, SO, SO and NH, or lower alkylene or lower alkenylene in which thehetero atom group may intervene； R is optionally substituted aryl；R is hydrogen, a halogen, hydroxy, optionally substituted loweralkyl etc； and R and Z part taken together forms a ring,to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.
