NII, TAKUYA,二井卓哉,HAGI, AKIFUMI,萩彰文,TSUBOTANI, YOSHIE,坪谷好惠
申请号：
TW107112457
公开号：
TWI675658B
申请日:
2018.04.11
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
An object of the present invention is to provide a composition that can be used as a novel anti-inflammatory agent. An inflammation such as stomatitis, oral mucositis, gingivitis, or pneumonia can be ameliorated and/or prevented by using a composition comprising olanexidine or a pharmacologically acceptable salt thereof. The composition of the present invention preferably further comprises a poloxamer which is a block copolymer consisting of a chain of polyoxypropylene (POP) and two chains of polyoxyethylene (POE) flanking the POP.本發明的課題是提供一種可用來做為新型抗炎症劑的組合物。藉由使用包含奧蘭西丁(olanexidine)或其藥理學上可接受的鹽的組合物，可以改善及/或預防口內炎、口腔黏膜炎、牙齦炎、肺炎等炎症。本發明的組合物較佳為更包含泊洛沙姆，是由聚氧丙烯鏈(POP)和夾著該POP的兩個聚氧乙烯鏈(POE)所構成的嵌段共聚物。
