The present invention is concerned with novel substituted indole derivatives of Formula (I) wherein R1, R2, R3, A1, A2, A3, Y and X have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.本發明係關於式(I)之新穎的經取代的吲哚衍生物其中R1、R2、R3、A1、A2、A3、Y和X具有申請專利範圍中所定義的意義。根據本發明的化合物可用作伽瑪分泌酶調節劑。本發明尚關於製備該等新穎化合物的方法、含該等化合物作為活性成分之醫藥組成物,以及該等化合物作為藥劑的用途。
