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Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
专利权人:
John Court;Janos Pitlik;Luc Farmer;Kevin Cottrell;Robert B. Perni;David Deininger
发明人:
David Deininger,John Court,Luc Farmer,Janos Pitlik,Kevin Cottrell,Robert B. Perni
申请号:
US12639162
公开号:
US08536136B2
申请日:
2009.12.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compounds of formula I:or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
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中国工程科技知识中心
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