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Inhibitors of Serine Proteases, Particularly HCV NS3-NS4A Protease
专利权人:
Vertex Pharmaceuticals Incorporated
发明人:
Cottrell, Kevin M.,Perni, Robert B.,Pitlik, Janos
申请号:
AU2011253940
公开号:
AU2011253940A1
申请日:
2011.12.09
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2011253940A120120112.pdf#####ABSTRACT The present invention relates to compounds of formula: (I) or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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