Castaigne, Jean-Paul,Demeule, Michel,Che, Christian,Regina, Anthony
申请号:
AU2010305284
公开号:
AU2010305284A1
申请日:
2010.10.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention is directed to conjugates that include a polypeptide capable of crossing the blood-brain barrier or entering one or more cell types attached to a transport vector, i.e., a compostion capable of transporting an agent (e.g., a therapeutic agent). In certain cases, the polypeptides are directly conjugated to a lipid or polymeric vector to allow targeted application of a therapeutic agent to treat, for example, a cancer, a neurodegenerative disease, or a lysosomal storage disorder.