METHOD FOR PREPARING OF LIPID BASED EXTRACTS HAVING VARYING CONCENTRATIONS OF ACTIVE MEDICAMENTS AND VARYING REDUCED LEVELS OF LIPID CONTENT AND PRODUCTS THEREOF
The invention relates to a method of preparing improved lipid based composition such as formulations of Snehas i.e. Tailams, Kerams, Ghritams, Yamakams, Trivrutams, Mahasnehams and other lipid extracts of the herbs and other materials such that there are ratio of drug to fat can be increased to varying higher percentage. The method of incorporating maximum amount of drug (polar) into a lipid carrier comprises of mixing the lipid formulation of Ayurveda, siddha, Unani systems of medicine with a polar/non-polar solvent fraction and passing it through a column packed with polar/non-polar adsorbent. The eluent containing polar medicament with low fat content is collected. This fraction contains maximum amount of drug in a lower quantity of the lipid base. Administering the improved lipid based composition of the present invention results in very small quantity of the fat being utilized to deliver therapeutically recommended or effective doses of synthetic or natural substance as drugs, cosmetics or nutraceuticals as the case maybe.
