The present invention advantageously provides a method and system for providing accurately localized, non-invasive radiation treatment for ocular melanoma or other intraocular indications through the completion of specified research tasks. The present invention further provides for dynamic localization of tumors associated with such indications. The system of the present invention includes the CYBERKNIFE system, a robust eye pupil tracking system, and an integrated software package to achieve intra-beam fractional tumor tracking during radiation delivery. The system may further include a mechanical phantom incorporated with a radiation dosimetry calibration kit for validation.