Javier Dotor Herrerías;Esperanza Feijoo Blanco;Francisco Borrás Cuesta
发明人:
Javier Dotor Herrerías,Francisco Borrás Cuesta,Esperanza Feijoo Blanco
申请号:
US12709895
公开号:
US08158589B2
申请日:
2010.02.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The described peptides possess the capacity to bind to Transforming Growth Factor TGF-β1 (TGF-β1), and are potential inhibitors of the biological activity of TGF-β1 through direct binding to this cytokine. These peptides can be used in the treatment of diseases or pathological alterations based on excessive or deregulated TGF-β1 expression, e.g., liver fibrosis, pulmonary fibrosis, corneal fibrosis and haze.