PROBLEM TO BE SOLVED: To provide a ritodrine hydrochloride injection formulation containing ritodrine hydrochloride having a specific concentration and a sulfite having a specific concentration, controlled to a specific pH and effective for suppressing formation of a threo-isomer and a sulfite adduct.SOLUTION: There is provided a ritodrine hydrochloride injectable formulation prepared by filling a plastic container with an injection liquid containing 5-15 mg/mL of ritodrine hydrochloride and 0.3-0.7 mg/mL of a sulfite and having a pH of 4.7-5.5, and sealing the container together with a deoxidation agent in a poorly oxygen-permeating packaging material.COPYRIGHT: (C)2012,JPO&INPIT【課題】特定の濃度の塩酸リトドリンと特定の濃度の亜硫酸塩類を含有し、特定のpHに調製した、トレオ体と亜硫酸付加物の生成を抑制する塩酸リトドリン注射製剤を提供する。【解決手段】塩酸リトドリン5~15mg/mLおよび亜硫酸塩類0.3~0.7mg/mLを含有し、pHが4.7~5.5である注射液をプラスチック製容器に充填し、脱酸素剤と共に酸素難透過性包材に封入されてなることを特徴とする塩酸リトドリン注射製剤。【選択図】図1
