Alcohol derivatives represented by the general formula (IV)； wherein: R 1 represents a substituted C 1 -C 12 alkyl group； a substituted C 2 -C 6 alkenyl group； a substituted amino group； a substituted C 1 -C 6 alkoxy group； a substituted C 1 -C 6 alkylthio group； a substituted carbamoyl group； a substituted sulfonamide group； or a substituted amide group； the ring A represents a saturated cyclic alkyl group with 5 to 7 carbon atoms； R 2 represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aromatic hydrocarbon group or a substituted or unsubstituted heterocyclic group； R 3 represents a hydrogen atom, a group represented by the general formula R 4 O- ； or a group represented by the general formula R 5 (R 6 )N-wherein R 4 represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aromatic hydrocarbon group or a substituted or unsubstituted heterocyclic group； R 5 and R 6 may be the same or different and each represents a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aromatic hydrocarbon group or a substituted or unsubstituted heterocyclic group, The cyclic carboxylic acid derivatives of formula (IV) are useful for the synthesis of cyclic amide derivatives useful as cathepsin K inhibitors.
