3-(((((2S,5R)-2-CARBAMOYL-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTAN-6-YL)OXY)SULFONYL)OXY)-2,2-DIMETHYLPROP NOATE DERIVATIVES AND RELATED COMPOUNDS AS PERORALLY ADMINISTERED PROFRUGS OF BETA-LACTAMASE INHIBITORS FOR TREATING BACTERIAL INFECTIONS
GORDON, Eric,FREUND, John,GALLOP, Mark,DUNCTON, Matthew
申请号：
SG11201909429V
公开号：
SG11201909429VA
申请日:
2018.05.02
申请国别(地区):
SG
年份:
2019
代理人:
摘要：
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 15 November 2018 (15.11.2018) WIPO I PCT omit VIII °nolo Holollm H H voila° oimIE (10) International Publication Number WO 2018/208557 Al (51) International Patent Classification: C07D 471/08 (2006.01) A61P 31/04 (2006.01) A61K 31/439 (2006.01) (21) International Application Number: PCT/US2018/030652 (22) International Filing Date: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) W O 20 18/ 208557 Al 02 May 2018 (02.05.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/504,523 10 May 2017 (10.05.2017) US 62/551,043 28 August 2017 (28.08.2017) US 15/934,497 23 March 2018 (23.03.2018) US (71) Applicant: ARIXA PHARMACEUTICALS, INC. [US/US]； 525 Univercity Ave., Suite 1350, Palo Alto, CA 94301 (US). (72) Inventors: GORDON, Eric, M.； 525 University Ave., Suite 1350, Palo Alto, CA 94301 (US). FREUND, John； 525 University Ave., Suite 1350, Palo Alto, CA 94301 (US). GALLOP, Mark, A.； 525 University Ave., Suite 1350, Pa- lo Alto, CA 94301 (US). DUNCTON, Matthew, Alexan- der, James； 525 University Ave., Suite 1350, Palo Alto, CA 94301 (US). (74) Agent: LAMBERT, William, R.； Sheppard Mullin Richter & Hampton LLP, 379 Lytton Ave., Palo Alto, CA 94301 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, T
