INTERNATIONAL APPLICATION PUBLISHED (19) World Intellectual Property Organization International Bureau UNDER THE PATENT COOPERATION TREATY (PCT) vitivio VIII otiolo Kan oimIE (10) International Publication Number WO 2018/226995 Al PCT (43) International Publication Date 13 December 2018 (13.12.2018) WIP0 I Armando； 3010 59th Street S, #115, Gulfport, Florida 33707 (US). (74) Agent: FAJKOWSKI, James E. et al.； K&L GATES LLP, State Street Financial Center, One Lincoln Street, Boston, Massachusetts 02111 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (51) International Patent Classification: A61B 18/20 (2006.01) (21) International Application Number: PCT/US2018/036516 (22) International Filing Date: 07 June 2018 (07.06.2018) English English (25) Filing Language: (26) Publication Language: (30) Priority Data: 62/516,665 07 June 2017 (07.06.2017) US (71) Applicant: CYNOSURE, INC. [US/US]； 5 Carlisle Road, Westford, Massachusetts 01886 (US). (72) Inventors: CHEN, Bo； 242 Mountain View Avenue, Mountain View, California 94041 (US). SIERRA, Rafael (54) Title: FAT REDUCTION AND IMPROVING SKIN LAXITY 306 303 FIG. 3 (57) : In part, the disclosure relates to systems and methods for applying treatment energy, e.g., electromagnetic radiation such as laser radiation, to body areas having bulges and fat deposits and loose skin. Methods and systems disclosed herein are surprisingly effective in generating a desirable temperature profile in a target
