METHODS OF MANUFACTURE AND SYNTHESIS OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR TARGETED IMAGING OF TUMORS

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专利权人:

ON TARGET LABORATORIES LLC

发明人:

KULARATNE, SUMITH, A. SA,‧庫拉拉特尼,GAGARE, PRAVIN P,‧嘉嘉裡,NOSHI, MOHAMMAD M,‧諾施

申请号：

HK16106296.0

公开号：

HK1218257A

申请日:

2016.06.02

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.

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