Viviana Gradinaru,Claire N. Bedbrook,Frances H. Arnold,Kevin K. Yang
申请号:
US16573321
公开号:
US20200087358A1
申请日:
2019.09.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are engineered light-sensitive proteins, for example channelrhodopsins and variants thereof. Also disclosed are compositions for expressing the light-sensitive proteins in cells, tissues, organs and subjects, and methods for using the light-sensitive proteins to, for example, enable minimally-invasive neuronal circuit interrogation in living organism, and treat neuronal and ocular disorders.